Tehran University of Medical Sciences The Research in Heart Yield and Translational Medicine (RHYTHM) 3115-7270 21 3 2026 05 24 249 252 Homa Ghaderian Assistant Professor of Cardiology, Cardiology Department, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, I.R. Iran Sahar Asl-Fallah Assistant Professor of Cardiology, Cardiology Department, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, I.R. Iran Soheil Mansourian Assistant Professor of Cardiovascular Surgery, Cardiovascular Surgery Department, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, I.R. Iran Ali Hosseinsabet Cardiology Department, Tehran Heart Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran 2025 09 26 2025 10 14 Left ventricular outflow tract obstruction is a presentation of subaortic membrane. Asymmetric septal hypertrophy is an uncommon echocardiographic finding in this condition. Nonetheless, it is a common presentation of hypertrophic cardiomyopathy. These 2 conditions can coexist in the same patient. We describe a woman with a significant obstructive subaortic membrane and asymmetric septal hypertrophy, with a final diagnosis of hypertrophic cardiomyopathy confirmed by cardiac magnetic resonance imaging. https://jthc.tums.ac.ir/index.php/jthc/article/view/2358 https://jthc.tums.ac.ir/index.php/jthc/article/download/2358/1279