Case Report

Catheter-Directed Thrombolysis in Acute Iliofemoral Deep Vein Thrombosis with or without Stenting: A Case Series

Abstract

Iliofemoral deep vein thrombosis (IFDVT) is a potentially devastating condition comprising a quarter of all cases of lower extremity DVT. It can lead to serious consequences such as pulmonary embolism, limb malperfusion, and post-thrombotic syndrome (PTS), which is a chronic sequela of IFDVT. We herewith present 18 IFDVT cases managed with catheter-directed thrombolysis at our hospital. Nine of these patients underwent stenting of the involved iliac veins. The remaining 9, who did not receive stenting, had a residual stenosis of more than 50% in the common femoral or iliac veins following the procedure. Based on a final residual stenosis of less than 50% in the iliac veins, we had 9 successful (patients with stenting) and 9 unsuccessful procedures (patients without stenting). In subsequent follow-ups at a median follow-up of 39.5 months, using the Villalta score, while only 2 out of the 9 patients who underwent stenting suffered PTS, 4 patients among the other 9 patients comprising the non-stenting group developed PTS. Our results support the notion that stenting might have a role in decreasing the PTS risk in patients undergoing catheter-directed thrombolysis.

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[CaVenT]

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[ATTRACT]

Vedantham, S., Goldhaber, S., Julian, J., Kahn, S., Jaff, M., Cohen, D., Magnuson, E., Razavi, M., Comerota, A., Gornik, H., Murphy, T., Lewis, L., Duncan, J., Nieters, P., Derfler, M., Filion, M., Gu, C., Kee, S., Schneider, J., Saad, N., Blinder, M., Moll, S., Sacks, D., Lin, J., Rundback, J., Garcia, M., Razdan, R., VanderWoude, E., Marques, V. and Kearon, C. (2017). Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis. New England Journal of Medicine, 377(23), pp.2240-2252.

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IssueVol 13 No 4 (2018): J Teh Univ Heart Ctr QRcode
SectionCase Report(s)
DOI https://doi.org/10.18502/jthc.v13i4.644
Keywords
Venous thrombosis Postthrombotic syndrome Stents

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How to Cite
1.
Haji Zeinali AM, Jenab Y, Ariannejad H, Kassaian SE, Alidoosti M, Aghajani H, Zafarghandi MR. Catheter-Directed Thrombolysis in Acute Iliofemoral Deep Vein Thrombosis with or without Stenting: A Case Series. J Tehran Heart Cent. 2018;13(4):186-190.