Original Article

Relationship between Color-Coded Anatomical M-Mode, Strain Imaging, and Tissue Doppler Imaging in Assessing Myocardial Asynchrony in Normal Subjects

Abstract

Background: This study aimed to compare the time-to-peak systolic contraction time (Tc) by color-coded anatomical M-mode (AMM), the time-to-peak systolic strain (Tst) by strain rate imaging (SRI), and the time-to-peak systolic velocity (Ts) by tissue Doppler imaging (TDI) in the left (LV) and right (RV) ventricular segments of normal subjects. We also sought to determine the relationship between these methods for defining asynchrony indices in normal subjects.
Methods: Conventional echocardiography, color-coded AMM, SRI, and TDI were performed on 44 healthy adult volunteers (at the Tehran Heart Center and Shariati Hospital) to measure Tc, Tst, and Ts for 12 LV and 2 RV segments at mid and basal levels. Additionally, delays and standard deviations (SDs) were measured in all 12 LV segments.
Results: In the assessed segments, Tc by AMM and Tst by SRI were significantly greater than Ts by TDI (P<0.001). No significant differences were noted between Tc and Tst in 8 LV and 2 RV segments (P<0.05). For the septal basal segment, the respective values were Ts=170.43±36.76 ms, Tst=372.34±72.21 ms, and Tc=374.19±42.76 ms. A moderate correlation was observed between AMM and SRI in assessing asynchrony and SD for all LV segments, but no correlation existed between AMM and TDI.
Conclusion: Tc by AMM and Tst by SRI were significantly higher than Ts by TDI in the LV and RV segments. There was no correlation between AMM and TDI in defining asynchrony indices.

1. Gorcsan J 3rd, Kanzaki H, Bazaz R, Dohi K, Schwartzman D. Usefulness of echocardiographic tissue synchronization imaging to predict acute response to cardiac resynchronization therapy. Am J Cardiol 2004;93:1178-1181.
2. Bax JJ, Marwick TH, Molhoek SG, Bleeker GB, van Erven L, Boersma E, Steendijk P, van der Wall EE, Schalij MJ. Left ventricular dyssynchrony predicts benefit of cardiac resynchronization therapy in patients with end-stage heart failure before pacemaker implantation. Am J Cardiol 2003;92:1238-1240.
3. Seo Y, Ito H, Nakatani S, Takami M, Naito S, Shiga T, Ando K, Wakayama Y, Aonuma K; J-CRT investigators. The role of echocardiography in predicting responders to cardiac resynchronization therapy. Circ J 2011;75:1156-1163.
4. Chung ES, Leon AR, Tavazzi L, Sun JP, Nihoyannopoulos P, Merlino J, Abraham WT, Ghio S, Leclercq C, Bax JJ, Yu CM, Gorcsan J 3rd, St John Sutton M, De Sutter J, Murillo J. Results of the Predictors of Response to CRT (PROSPECT) trial. Circulation 2008;117:2608-2616.
5. Strotmann JM, Kvitting JP, Wilkenshoff UM, Wranne B, Hatle L, Sutherland GR. Anatomic M-mode echocardiography: A new approach to assess regional myocardial function--A comparative in vivo and in vitro study of both fundamental and second harmonic imaging modes. J Am Soc Echocardiogr 1999;12:300-307.
6. Mele D, Pedini I, Alboni P, Levine RA. Anatomic M-mode: a new technique for quantitative assessment of left ventricular size and function. Am J Cardiol 1998;81:82G-85G.
7. Thijssen JM, de Korte CL. Cardiological Ultrasound Imaging. Curr Pharm Des 2014;20:6150-6161.
8. Oyama MA, Sisson DD. Assessment of cardiac chamber size using anatomic M-mode. Vet Radiol Ultrasound 2005;46:331-336.
9. Katsuki K, Nakatani S, Kanzaki H, Hanatani A, Tanaka N, Nakasone I, Masuda Y, Yamagishi M, Miyatake K. Clinical validation of accuracy of anatomical M-mode measurements: effect of harmonic imaging. J Cardiol 2001;37:35-42.
10. Sadeghian H, Ahmadi F, Lotfi-Tokaldany M, Kazemisaeid A, Fathollahi MS, Goodarzynejad H. Ventricular asynchrony of time-to-peak systolic velocity in structurally normal heart by tissue Doppler imaging. Echocardiography 2010;27:823-830.
11. Nikdoust F, Sadeghian H, Lotfi-Tokaldany M. Regional quantification of left atrial early diastolic strain in two groups of patients with mitral stenosis: normal sinus rhythm vs atrial fibrillation. Echocardiography 2016;33:1818-1822.
12. Sakamaki F, Seo Y, Atsumi A, Yamamoto M, Machino-Ohtsuka T, Kawamura R, Yamasaki H, Igarashi M, Sekiguchi Y, Ishizu T, Aonuma K. Novel dyssynchrony evaluation by M-mode imaging in left bundle branch block and the application to predict responses for cardiac resynchronization therapy. J Cardiol 2014;64:199-206.
13. Burgess MI, Jenkins C, Chan J, Marwick TH. Measurement of left ventricular dyssynchrony in patients with ischaemic cardiomyopathy: a comparison of real-time three-dimensional and tissue Doppler echocardiography. Heart 2007;93:1191-1196.
Files
IssueVol 19 No 4 (2024): J Teh Univ Heart Ctr QRcode
SectionOriginal Article(s)
DOI https://doi.org/10.18502/jthc.v19i4.17613
Keywords
Echocardiography Methods Anatomical M-mode Tissue doppler imaging Myocardial asynchrony Strain rate imaging
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Masoumi MA, Lotfi Tokaldany M, Sarhangzadeh S, Siavosh P, Sadeghian H. Relationship between Color-Coded Anatomical M-Mode, Strain Imaging, and Tissue Doppler Imaging in Assessing Myocardial Asynchrony in Normal Subjects. J Tehran Heart Cent. 2024;19(4):270-275.